One fundamental problem is to construct equivalences between manifolds; another is to construct invariants. Of course these complementary problems should be related. This talk will be general discussion of some developments in these directions. We recall the special property of the curvature tensor of a Riemannian 3-manifold which underpins the Geometrisation Theorem. Then we discuss Riemannian and other structures in higher dimensions. We give an account of work of Gromov, Taubes, and others, using holomorphic spheres in symplectic 4-manifolds, and of results of Friedl, and Vidussi, and others, on fibred 3-manifolds and symplectic structures.